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Peptide record

TPDB10898

Antibacterial Hemolysis Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB10898
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
GGLRSLGRKALRAWKKYGPIIVPIIRI
Physicochemical Analysis
C142H243N43O30
NDCEQHMFT
I
3032.76
12.42
7
0
13
+7
0.99
0.156
133.70
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6990
230.48
2
Residue Composition
number
2
A
4
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
5
I
3
L
3
K
0
M
0
F
2
P
1
S
0
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 5 L: 3 K: 3 M: 0 F: 0 P: 2 S: 1 T: 0 W: 1 Y: 1 V: 1
Chemical Descriptors
27
C142H243N43O30
3032.76
12.42
+7
0.99
0.156
Evidence Records 2 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
20% Hemolysis | 20 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function study of cathelicidin-derived bovine antimicrobial peptide BMAP-28: design of its cell-selective analogs by amino acid substitutions in the heptad repeat sequences. | Biochim Biophys Acta | 2009
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis