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Peptide record

TPDB10863

Antibacterial Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10863
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 26-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GRFKRFRKKAKKLFKKLSPVIPLLHL
Physicochemical Analysis
C152H258N44O28
NDCEQMTWY
K
3150.00
12.73
11
0
11
+10
4.76
-0.404
105.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
3
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
5
L
7
K
0
M
3
F
2
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 5 K: 7 M: 0 F: 3 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
26
C152H258N44O28
3150.00
12.73
+10
4.76
-0.404
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
0% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of nontoxic analogues of cathelicidin-derived bovine antimicrobial peptide BMAP-27: the role of leucine as well as phenylalanine zipper sequences in determining its toxicity. | Biochemistry | 2009