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Peptide record

TPDB10858

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10858
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SIITMTKEAKLPQSWKQIACRLYNTC
Physicochemical Analysis
C133H220N36O38S3
DGHFV
IKT
3027.61
9.63
4
1
10
+3
2.62
-0.235
82.69
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
7115
235.00
11
Residue Composition
number
2
A
1
R
1
N
0
D
2
C
1
E
2
Q
0
G
0
H
3
I
2
L
3
K
1
M
0
F
1
P
2
S
3
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 1 D: 0 C: 2 E: 1 Q: 2 G: 0 H: 0 I: 3 L: 2 K: 3 M: 1 F: 0 P: 1 S: 2 T: 3 W: 1 Y: 1 V: 0
Chemical Descriptors
26
C133H220N36O38S3
3027.61
9.63
+3
2.62
-0.235
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
60 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli ATCC25922 (MIC 60 ug/ml), B. dysenteriae (MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (M
Evidence 2 Activity

Activity

MIC
Antibacterial
60 µg/mL

Target

B. dysenteriae

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC25922 (MIC 60 ug/ml), B. dysenteriae (MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (MIC 30 ug/ml), and C. albicans A
Evidence 3 Activity

Activity

MIC
Antibacterial
15 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC25922 (MIC 60 ug/ml), B. dysenteriae (MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (MIC 30 ug/ml), and C. albicans ATCC2002 (MIC 30 ug/ml).
Evidence 4 Activity

Activity

MIC
Antibacterial
30 µg/mL

Target

H. pylori NCTC11637

Source & Reference

dbAMP DRAMP

Other

CC25922 (MIC 60 ug/ml), B. dysenteriae (MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (MIC 30 ug/ml), and C. albicans ATCC2002 (MIC 30 ug/ml).
Evidence 5 Activity

Activity

MIC
Antibacterial
30 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP DRAMP

Other

MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (MIC 30 ug/ml), and C. albicans ATCC2002 (MIC 30 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
60 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli ATCC25922 (MIC 60 ug/ml), B. dysenteriae (MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (M
Evidence 7 Activity

Activity

MIC
Antifungal
60 µg/mL

Target

B. dysenteriae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC25922 (MIC 60 ug/ml), B. dysenteriae (MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (MIC 30 ug/ml), and C. albicans A
Evidence 8 Activity

Activity

MIC
Antifungal
15 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC25922 (MIC 60 ug/ml), B. dysenteriae (MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (MIC 30 ug/ml), and C. albicans ATCC2002 (MIC 30 ug/ml).
Evidence 9 Activity

Activity

MIC
Antifungal
30 µg/mL

Target

H. pylori NCTC11637

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

CC25922 (MIC 60 ug/ml), B. dysenteriae (MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (MIC 30 ug/ml), and C. albicans ATCC2002 (MIC 30 ug/ml).
Evidence 10 Activity

Activity

MIC
Antifungal
30 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (MIC 30 ug/ml), and C. albicans ATCC2002 (MIC 30 ug/ml).
Evidence 11 Activity

Activity

MIC
Antiparasitic
60 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli ATCC25922 (MIC 60 ug/ml), B. dysenteriae (MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (M
Evidence 12 Activity

Activity

MIC
Antiparasitic
60 µg/mL

Target

B. dysenteriae

Source & Reference

DRAMP

Other

Active against E. coli ATCC25922 (MIC 60 ug/ml), B. dysenteriae (MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (MIC 30 ug/ml), and C. albicans A
Evidence 13 Activity

Activity

MIC
Antiparasitic
15 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

DRAMP

Other

Active against E. coli ATCC25922 (MIC 60 ug/ml), B. dysenteriae (MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (MIC 30 ug/ml), and C. albicans ATCC2002 (MIC 30 ug/ml).
Evidence 14 Activity

Activity

MIC
Antiparasitic
30 µg/mL

Target

H. pylori NCTC11637

Source & Reference

DRAMP

Other

CC25922 (MIC 60 ug/ml), B. dysenteriae (MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (MIC 30 ug/ml), and C. albicans ATCC2002 (MIC 30 ug/ml).
Evidence 15 Activity

Activity

MIC
Antiparasitic
30 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

DRAMP

Other

MIC 60 ug/ml), S. aureus ATCC2592 (MIC 15 ug/ml), H. pylori NCTC11637 (MIC 30 ug/ml), and C. albicans ATCC2002 (MIC 30 ug/ml).
Evidence 16 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:17764786] It has little hemolytic activity on red blood cells even with peptide concentration up to 200 µg/ml

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2007 Oct 28(10):2069-2074.