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Peptide record

TPDB10855

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10855
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF pep-lab AFP-GFuse Antifungipept CAFPdb APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLVTSLIKGAGKLLGGLFGSVTGGQS
Physicochemical Analysis
C108H185N29O33
RNDCEHMPWY
G
2417.83
10.60
2
0
10
+2
-0.96
0.700
116.15
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
6
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
1
Q
8
G
0
H
1
I
5
L
2
K
0
M
1
F
0
P
3
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 8 H: 0 I: 1 L: 5 K: 2 M: 0 F: 1 P: 0 S: 3 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
26
C108H185N29O33
2417.83
10.60
+2
-0.96
0.700
Evidence Records 3 records
Evidence 1 Activity

Activity

30% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
30% Hemolysis | 50 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Membrane association, electrostatic sequestration, and cytotoxicity of Gly-Leu-rich peptide orthologs with differing functions. | Biochemistry | 2004
Evidence 2 Activity

Activity

70% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
70% Hemolysis | 100 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Membrane association, electrostatic sequestration, and cytotoxicity of Gly-Leu-rich peptide orthologs with differing functions. | Biochemistry | 2004
Evidence 3 Hemolysis

Source & Reference

APD_complete APD_hemolytic HemoPI PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.