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Peptide record

TPDB10849

Antibacterial Antifungal Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10849
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GTFIKQQRKQKQQRHHTSGTRKRMAK
Physicochemical Analysis
C133H230N52O36S1
NDCELPWYV
QK
3165.68
12.89
11
0
4
+9
11.74
-2.081
18.85
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
9
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
0
E
5
Q
2
G
2
H
1
I
0
L
5
K
1
M
1
F
0
P
1
S
3
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 5 G: 2 H: 2 I: 1 L: 0 K: 5 M: 1 F: 1 P: 0 S: 1 T: 3 W: 0 Y: 0 V: 0
Chemical Descriptors
26
C133H230N52O36S1
3165.68
12.89
+9
11.74
-2.081
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Escherichia coli ATCC 11775

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli ATCC 11775 (MIC 64 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here.
Evidence 2 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Escherichia coli ATCC 11775

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli ATCC 11775 (MIC 64 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here.
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus). | PLoS One | 2016