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Peptide record

TPDB10845

Antibacterial Antifungal Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10845
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
ASITHVKNRGKYIYMHLKFRKTNVLI
Physicochemical Analysis
C144H236N42O34S1
DCEQPW
K
3131.78
11.06
8
0
12
+6
3.44
-0.277
101.15
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
2980
95.15
7
Residue Composition
number
1
A
2
R
2
N
0
D
0
C
0
E
0
Q
1
G
2
H
3
I
2
L
4
K
1
M
1
F
0
P
1
S
2
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 1 R: 2 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 2 I: 3 L: 2 K: 4 M: 1 F: 1 P: 0 S: 1 T: 2 W: 0 Y: 2 V: 2
Chemical Descriptors
26
C144H236N42O34S1
3131.78
11.06
+6
3.44
-0.277
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Escherichia coli ATCC 11775

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli ATCC 11775 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 16 ug/ml). Note tha
Evidence 2 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Active against E. coli ATCC 11775 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 16 ug/ml). Note that the mature sequence may differ from
Evidence 3 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP

Other

ctive against E. coli ATCC 11775 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 16 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here.
Evidence 4 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Escherichia coli ATCC 11775

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli ATCC 11775 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 16 ug/ml). Note tha
Evidence 5 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 11775 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 16 ug/ml). Note that the mature sequence may differ from
Evidence 6 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ctive against E. coli ATCC 11775 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 16 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here.
Evidence 7 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus). | PLoS One | 2016