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Peptide record

TPDB10829

Antibacterial Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10829
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 26-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
QLQGKQVSGEVVQKVLQELIQSVAKP
Physicochemical Analysis
C125H217N35O39
RNDCHMFTWY
Q
2834.31
9.76
3
2
10
+1
9.41
-0.192
119.62
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
8
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
2
E
6
Q
2
G
0
H
1
I
3
L
3
K
0
M
0
F
1
P
2
S
0
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 2 Q: 6 G: 2 H: 0 I: 1 L: 3 K: 3 M: 0 F: 0 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 5
Chemical Descriptors
26
C125H217N35O39
2834.31
9.76
+1
9.41
-0.192
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Tilapia erythrocytes

Target

Tilapia erythrocytes

Source & Reference

NA
DBAASP
Five different piscidins from Nile tilapia, Oreochromis niloticus: analysis of their expressions and biological functions. | PLoS One | 2012
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Five different piscidins from Nile tilapia, Oreochromis niloticus: analysis of their expressions and biological functions. | PLoS One | 2012
Evidence 3 Activity

Activity

10% Killing
Toxicity
80 µg/mL
Cytotoxic
10% Killing | 80 | µg/mL | target cell: Tilapia ovary TO2 cells

Target

Tilapia ovary TO2 cells

Source & Reference

NA
DBAASP
Five different piscidins from Nile tilapia, Oreochromis niloticus: analysis of their expressions and biological functions. | PLoS One | 2012