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Peptide record

TPDB10827

Antibacterial Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10827
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KWKSFLRTLKSPAKTVFHTALKAISS
Physicochemical Analysis
C138H225N37O34
NDCEQGMY
K
2946.53
11.85
7
0
11
+6
1.57
-0.150
82.69
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
186.66
7
Residue Composition
number
3
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
3
L
5
K
0
M
2
F
1
P
4
S
3
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 3 K: 5 M: 0 F: 2 P: 1 S: 4 T: 3 W: 1 Y: 0 V: 1
Chemical Descriptors
26
C138H225N37O34
2946.53
11.85
+6
1.57
-0.150
Evidence Records 2 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | >128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of proline residues on the antibacterial and synergistic activities of alpha-helical peptides. | Biochemistry | 1999
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis