Back to search

Peptide record

TPDB10826

Antibacterial Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10826
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KWKSFLRTFKSPVRTVFHTALKPISS
Physicochemical Analysis
C145H229N39O34
NDCEQGMY
KS
3062.65
12.44
7
0
10
+6
1.68
-0.250
71.15
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
179.58
7
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
2
L
4
K
0
M
3
F
2
P
4
S
3
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 2 K: 4 M: 0 F: 3 P: 2 S: 4 T: 3 W: 1 Y: 0 V: 2
Chemical Descriptors
26
C145H229N39O34
3062.65
12.44
+6
1.68
-0.250
Evidence Records 2 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | >128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of proline residues on the antibacterial and synergistic activities of alpha-helical peptides. | Biochemistry | 1999
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis