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Peptide record

TPDB10811

Antibacterial Antifungal standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10811
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 26-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RRRPRPPYLPRPRPPPFFPPRLPPRI
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C153H242N50O28
ANDCEQGHKMSTWV
P
3229.92
12.88
8
0
6
+8
3.80
-1.492
45.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
0.46
1
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
2
L
0
K
0
M
2
F
12
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 0 M: 0 F: 2 P: 12 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
26 reviewed residue count
C153H242N50O28 sequence-only estimate (linear, free termini)
3229.92 sequence-only estimate (linear, free termini)
12.88 sequence-only estimate (linear, free termini)
+8 sequence-only estimate (linear, free termini)
3.80 sequence-only estimate (linear, free termini)
-1.492 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against E. coli (MBC 2.5 uM) and B. globigii (MBC 5 uM).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against E. coli (MBC 2.5 uM) and B. globigii (MBC 5 uM).