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Peptide record

TPDB10809

Antibacterial Antifungal standard
26 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10809
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 26-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
APKAMHSAKKFGKAFVGEIMLQKKGI
Physicochemical Analysis
C129H215N35O31S2
RNDCTWY
K
2816.46
10.82
7
1
12
+5
5.60
-0.138
71.54
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
1
E
1
Q
3
G
1
H
2
I
1
L
6
K
2
M
2
F
1
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 3 H: 1 I: 2 L: 1 K: 6 M: 2 F: 2 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
26
C129H215N35O31S2
2816.46
10.82
+5
5.60
-0.138
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against Gram- E. coli (MIC 64 ug/ml), P. putida (MIC 64 ug/ml), S. enteritidis (MIC 32 ug/ml), Gram+ B. subtilis (MIC 64 ug/ml
Evidence 2 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

P. putida

Source & Reference

dbAMP

Other

active against Gram- E. coli (MIC 64 ug/ml), P. putida (MIC 64 ug/ml), S. enteritidis (MIC 32 ug/ml), Gram+ B. subtilis (MIC 64 ug/ml), S. aureus (MIC 64 ug/ml
Evidence 3 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

S. enteritidis

Source & Reference

dbAMP

Other

active against Gram- E. coli (MIC 64 ug/ml), P. putida (MIC 64 ug/ml), S. enteritidis (MIC 32 ug/ml), Gram+ B. subtilis (MIC 64 ug/ml), S. aureus (MIC 64 ug/ml), S.mutans (MIC 128 ug/ml), fu
Evidence 4 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

B. subtilis

Source & Reference

dbAMP

Other

m- E. coli (MIC 64 ug/ml), P. putida (MIC 64 ug/ml), S. enteritidis (MIC 32 ug/ml), Gram+ B. subtilis (MIC 64 ug/ml), S. aureus (MIC 64 ug/ml), S.mutans (MIC 128 ug/ml), fungi C. neoformans (MIC 16 ug/ml),
Evidence 5 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

. putida (MIC 64 ug/ml), S. enteritidis (MIC 32 ug/ml), Gram+ B. subtilis (MIC 64 ug/ml), S. aureus (MIC 64 ug/ml), S.mutans (MIC 128 ug/ml), fungi C. neoformans (MIC 16 ug/ml), S. cerevisiae (MIC 32 ug/m
Evidence 6 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

S.mutans

Source & Reference

dbAMP

Other

. enteritidis (MIC 32 ug/ml), Gram+ B. subtilis (MIC 64 ug/ml), S. aureus (MIC 64 ug/ml), S.mutans (MIC 128 ug/ml), fungi C. neoformans (MIC 16 ug/ml), S. cerevisiae (MIC 32 ug/ml), and C. albicans (MIC 3
Evidence 7 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

C. neoformans

Source & Reference

dbAMP

Other

am+ B. subtilis (MIC 64 ug/ml), S. aureus (MIC 64 ug/ml), S.mutans (MIC 128 ug/ml), fungi C. neoformans (MIC 16 ug/ml), S. cerevisiae (MIC 32 ug/ml), and C. albicans (MIC 32 ug/ml).
Evidence 8 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

S. cerevisiae

Source & Reference

dbAMP

Other

, S. aureus (MIC 64 ug/ml), S.mutans (MIC 128 ug/ml), fungi C. neoformans (MIC 16 ug/ml), S. cerevisiae (MIC 32 ug/ml), and C. albicans (MIC 32 ug/ml).
Evidence 9 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

Candida albicans

Source & Reference

dbAMP

Other

ns (MIC 128 ug/ml), fungi C. neoformans (MIC 16 ug/ml), S. cerevisiae (MIC 32 ug/ml), and C. albicans (MIC 32 ug/ml).
Evidence 10 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against Gram- E. coli (MIC 64 ug/ml), P. putida (MIC 64 ug/ml), S. enteritidis (MIC 32 ug/ml), Gram+ B. subtilis (MIC 64 ug/ml
Evidence 11 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

P. putida

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against Gram- E. coli (MIC 64 ug/ml), P. putida (MIC 64 ug/ml), S. enteritidis (MIC 32 ug/ml), Gram+ B. subtilis (MIC 64 ug/ml), S. aureus (MIC 64 ug/ml
Evidence 12 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

S. enteritidis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against Gram- E. coli (MIC 64 ug/ml), P. putida (MIC 64 ug/ml), S. enteritidis (MIC 32 ug/ml), Gram+ B. subtilis (MIC 64 ug/ml), S. aureus (MIC 64 ug/ml), S.mutans (MIC 128 ug/ml), fu
Evidence 13 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

m- E. coli (MIC 64 ug/ml), P. putida (MIC 64 ug/ml), S. enteritidis (MIC 32 ug/ml), Gram+ B. subtilis (MIC 64 ug/ml), S. aureus (MIC 64 ug/ml), S.mutans (MIC 128 ug/ml), fungi C. neoformans (MIC 16 ug/ml),
Evidence 14 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

. putida (MIC 64 ug/ml), S. enteritidis (MIC 32 ug/ml), Gram+ B. subtilis (MIC 64 ug/ml), S. aureus (MIC 64 ug/ml), S.mutans (MIC 128 ug/ml), fungi C. neoformans (MIC 16 ug/ml), S. cerevisiae (MIC 32 ug/m
Evidence 15 Activity

Activity

MIC
Antifungal
128 µg/mL

Target

S.mutans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

. enteritidis (MIC 32 ug/ml), Gram+ B. subtilis (MIC 64 ug/ml), S. aureus (MIC 64 ug/ml), S.mutans (MIC 128 ug/ml), fungi C. neoformans (MIC 16 ug/ml), S. cerevisiae (MIC 32 ug/ml), and C. albicans (MIC 3
Evidence 16 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

C. neoformans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

am+ B. subtilis (MIC 64 ug/ml), S. aureus (MIC 64 ug/ml), S.mutans (MIC 128 ug/ml), fungi C. neoformans (MIC 16 ug/ml), S. cerevisiae (MIC 32 ug/ml), and C. albicans (MIC 32 ug/ml).
Evidence 17 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

S. cerevisiae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

, S. aureus (MIC 64 ug/ml), S.mutans (MIC 128 ug/ml), fungi C. neoformans (MIC 16 ug/ml), S. cerevisiae (MIC 32 ug/ml), and C. albicans (MIC 32 ug/ml).
Evidence 18 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ns (MIC 128 ug/ml), fungi C. neoformans (MIC 16 ug/ml), S. cerevisiae (MIC 32 ug/ml), and C. albicans (MIC 32 ug/ml).