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Peptide record

TPDB10789

Antibacterial Anticancer Antifungal Antiviral Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10789
Antibacterial Anticancer Antifungal Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
HTASDAAAAAALTAANAAAAAAASMA
Physicochemical Analysis
C90H149N29O34S1
RCEQGIKFPWYV
A
2213.41
4.94
1
1
19
-1
-0.53
0.888
80.38
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
5
Residue Composition
number
17
A
0
R
1
N
1
D
0
C
0
E
0
Q
0
G
1
H
0
I
1
L
0
K
1
M
0
F
0
P
2
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 17 R: 0 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 1 K: 0 M: 1 F: 0 P: 0 S: 2 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
26
C90H149N29O34S1
2213.41
4.94
-1
-0.53
0.888
Evidence Records 4 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structural and functional characterization of a multifunctional alanine-rich peptide analogue from Pleuronectes americanus. | PLoS One | 2012
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Structural and functional characterization of a multifunctional alanine-rich peptide analogue from Pleuronectes americanus. | PLoS One | 2012
Evidence 3 Activity

Activity

50% Cell death
Toxicity
>400 µg/mL
Cytotoxic
50% Cell death | >400 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Linear Antimicrobial Peptides With Activity Against Herpes Simplex Virus 1 and Aichi Virus | Biopolymers | 2017
Evidence 4 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Biopolymers. 2017 Mar 108(2).