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Peptide record

TPDB10785

Antibacterial Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10785
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 26-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GWLQLALHLLQLGLHLLQLALQLRRR
Physicochemical Analysis
C143H242N44O31
NDCEIKMFPSTYV
L
3073.77
12.70
5
0
15
+3
-2.22
0.523
187.69
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
178.93
4
Residue Composition
number
2
A
3
R
0
N
0
D
0
C
0
E
4
Q
2
G
2
H
0
I
12
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 4 G: 2 H: 2 I: 0 L: 12 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
26
C143H242N44O31
3073.77
12.70
+3
-2.22
0.523
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
5% Hemolysis | 100 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Designing cell-aggregating peptides without cytotoxicity. | Biomacromolecules | 2014