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Peptide record

TPDB10784

Antibacterial Anticancer Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10784
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
GVWGIAKIAGKVLGNILPHVFSSNQS
Physicochemical Analysis
C124H198N34O33
RDCEMTY
G
2693.14
10.60
3
0
12
+2
0.08
0.465
116.15
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
204.22
6
Residue Composition
number
2
A
0
R
2
N
0
D
0
C
0
E
1
Q
4
G
1
H
3
I
2
L
2
K
0
M
1
F
1
P
3
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 1 G: 4 H: 1 I: 3 L: 2 K: 2 M: 0 F: 1 P: 1 S: 3 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
26
C124H198N34O33
2693.14
10.60
+2
0.08
0.465
Evidence Records 8 records
Evidence 1 Activity

Activity

0.9±1.5% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
0.9±1.5% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Peptidoglycan potentiates the membrane disrupting effect of the carboxyamidated form of DMS-DA6, a Gram-positive selective antimicrobial peptide isolated from Pachymedusa dacnicolor skin. | PLoS One | 2018
Evidence 2 Activity

Activity

7.4±5.5% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
7.4±5.5% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Peptidoglycan potentiates the membrane disrupting effect of the carboxyamidated form of DMS-DA6, a Gram-positive selective antimicrobial peptide isolated from Pachymedusa dacnicolor skin. | PLoS One | 2018
Evidence 3 Activity

Activity

0±2.8% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
0±2.8% Hemolysis | 10 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Peptidoglycan potentiates the membrane disrupting effect of the carboxyamidated form of DMS-DA6, a Gram-positive selective antimicrobial peptide isolated from Pachymedusa dacnicolor skin. | PLoS One | 2018
Evidence 4 Activity

Activity

5.4±3.5% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
5.4±3.5% Hemolysis | 50 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Peptidoglycan potentiates the membrane disrupting effect of the carboxyamidated form of DMS-DA6, a Gram-positive selective antimicrobial peptide isolated from Pachymedusa dacnicolor skin. | PLoS One | 2018
Evidence 5 Activity

Activity

1.2±1.8% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
1.2±1.8% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Peptidoglycan potentiates the membrane disrupting effect of the carboxyamidated form of DMS-DA6, a Gram-positive selective antimicrobial peptide isolated from Pachymedusa dacnicolor skin. | PLoS One | 2018
Evidence 6 Activity

Activity

3.7±3.3% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
3.7±3.3% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Peptidoglycan potentiates the membrane disrupting effect of the carboxyamidated form of DMS-DA6, a Gram-positive selective antimicrobial peptide isolated from Pachymedusa dacnicolor skin. | PLoS One | 2018
Evidence 7 Activity

Activity

0±1.1% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
0±1.1% Hemolysis | 10 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Peptidoglycan potentiates the membrane disrupting effect of the carboxyamidated form of DMS-DA6, a Gram-positive selective antimicrobial peptide isolated from Pachymedusa dacnicolor skin. | PLoS One | 2018
Evidence 8 Activity

Activity

4.7±5.6% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
4.7±5.6% Hemolysis | 50 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Peptidoglycan potentiates the membrane disrupting effect of the carboxyamidated form of DMS-DA6, a Gram-positive selective antimicrobial peptide isolated from Pachymedusa dacnicolor skin. | PLoS One | 2018