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Peptide record

TPDB10777

Antibacterial Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10777
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 26-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FLGGLIKIVPAMICAVTKKCHHHHHH
Physicochemical Analysis
C133H211N41O28S3
RNDEQSWY
H
2928.58
9.80
9
0
11
+3
5.25
0.338
105.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.27
3
Residue Composition
number
2
A
0
R
0
N
0
D
2
C
0
E
0
Q
2
G
6
H
3
I
2
L
3
K
1
M
1
F
1
P
0
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 2 H: 6 I: 3 L: 2 K: 3 M: 1 F: 1 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
26
C133H211N41O28S3
2928.58
9.80
+3
5.25
0.338
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 62.5 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Secretory ranalexin produced in recombinant Pichia pastoris exhibits additive or synergistic bactericidal activity when used in combination with polymyxin B or linezolid against multi-drug resistant bacteria. | Biotechnol J | 2014
Evidence 2 Activity

Activity

53% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
53% Hemolysis | 250 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Secretory ranalexin produced in recombinant Pichia pastoris exhibits additive or synergistic bactericidal activity when used in combination with polymyxin B or linezolid against multi-drug resistant bacteria. | Biotechnol J | 2014