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Peptide record

TPDB10773

Antibacterial Antifungal Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10773
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KWKLWKKIEKWGQGIGAVLKWLTTWL
Physicochemical Analysis
C159H242N38O32
RNDCHMFPSY
K
3197.91
10.82
6
1
13
+5
-3.36
-0.281
105.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
27500
859.94
3
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
1
Q
3
G
0
H
2
I
4
L
6
K
0
M
0
F
0
P
0
S
2
T
5
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 3 H: 0 I: 2 L: 4 K: 6 M: 0 F: 0 P: 0 S: 0 T: 2 W: 5 Y: 0 V: 1
Chemical Descriptors
26
C159H242N38O32
3197.91
10.82
+5
-3.36
-0.281
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
10 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 10 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cecropin A-melittin mutant with improved proteolytic stability and enhanced antimicrobial activity against bacteria and fungi associated with gastroenteritis in vitro. | Biochem Biophys Res Commun | 2014
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>300 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >300 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cecropin A-melittin mutant with improved proteolytic stability and enhanced antimicrobial activity against bacteria and fungi associated with gastroenteritis in vitro. | Biochem Biophys Res Commun | 2014