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Peptide record

TPDB10764

Antibacterial Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10764
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
RVKRVWPLVIRTVIALYNLYRAIKKK
Physicochemical Analysis
C152H258N44O31
DCEQGHMFS
RKV
3198.00
12.01
8
0
15
+8
1.81
0.092
142.31
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
8480
265.17
4
Residue Composition
number
2
A
4
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
3
L
4
K
0
M
0
F
1
P
0
S
1
T
1
W
2
Y
4
V
Amino Acid Distribution
A: 2 R: 4 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 3 K: 4 M: 0 F: 0 P: 1 S: 0 T: 1 W: 1 Y: 2 V: 4
Chemical Descriptors
26
C152H258N44O31
3198.00
12.01
+8
1.81
0.092
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
3 µM
Hemolytic Cytotoxic
50% Hemolysis | 3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken | FASEB J | 2006
Evidence 2 Activity

Activity

50% Cell death
Toxicity
15 µM
Cytotoxic
50% Cell death | 15 | µM | target cell: Madin-Darby canine kidney cells

Target

Madin-Darby canine kidney cells

Source & Reference

NA
DBAASP
Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken | FASEB J | 2006
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis