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Peptide record

TPDB10763

Antibacterial Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10763
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
RVKRVWKLVIRLVKALYKLYRAIKKK
Physicochemical Analysis
C157H274N46O29
NDCEQGHMFPST
K
3270.19
12.04
11
0
15
+11
3.52
-0.162
142.31
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
8480
259.31
2
Residue Composition
number
2
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
4
L
7
K
0
M
0
F
0
P
0
S
0
T
1
W
2
Y
4
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 4 K: 7 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 4
Chemical Descriptors
26
C157H274N46O29
3270.19
12.04
+11
3.52
-0.162
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
1 µM
Hemolytic Cytotoxic
50% Hemolysis | 1 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken | FASEB J | 2006
Evidence 2 Activity

Activity

50% Cell death
Toxicity
11 µM
Cytotoxic
50% Cell death | 11 | µM | target cell: Madin-Darby canine kidney cells

Target

Madin-Darby canine kidney cells

Source & Reference

NA
DBAASP
Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken | FASEB J | 2006
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis