Peptide record

TPDB10762

Antibacterial Antifungal Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10762
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RRRFVAQQNAIHSRVSRQVPTLSNSV
Physicochemical Analysis
C127H216N48O37
DCEGKMWY
R
3007.41
13.00
6
0
9
+5
6.64
-0.662
82.31
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
10
Residue Composition
number
2
A
5
R
2
N
0
D
0
C
0
E
3
Q
0
G
1
H
1
I
1
L
0
K
0
M
1
F
1
P
4
S
1
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 2 R: 5 N: 2 D: 0 C: 0 E: 0 Q: 3 G: 0 H: 1 I: 1 L: 1 K: 0 M: 0 F: 1 P: 1 S: 4 T: 1 W: 0 Y: 0 V: 4
Chemical Descriptors
26
C127H216N48O37
3007.41
13.00
+5
6.64
-0.662
Evidence Records 1 records
Evidence 1 Activity

Activity

1% Hemolysis
Toxicity
300 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 300 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Generation of novel cationic antimicrobial peptides from natural non-antimicrobial sequences by acid-amide substitution. | Ann Clin Microbiol Antimicrob | 2011