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Peptide record

TPDB10759

Antibacterial Antifungal Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10759
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RRGGGLELALAKDGWALMLDLGAGRR
Physicochemical Analysis
C119H202N40O33S1
NCQHIFPSTYV
GL
2753.22
11.15
5
3
12
+2
2.65
-0.146
105.38
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
199.77
0
Residue Composition
number
4
A
4
R
0
N
2
D
0
C
1
E
0
Q
6
G
0
H
0
I
6
L
1
K
1
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 4 N: 0 D: 2 C: 0 E: 1 Q: 0 G: 6 H: 0 I: 0 L: 6 K: 1 M: 1 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
26
C119H202N40O33S1
2753.22
11.15
+2
2.65
-0.146
Evidence Records 3 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
15 µM
Hemolytic Cytotoxic
20% Hemolysis | 15 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Beta-sheet pore-forming peptides selected from a rational combinatorial library: mechanism of pore formation in lipid vesicles and activity in biological membranes. | Biochemistry | 2007
Evidence 2 Activity

Activity

5% Hemolysis
Toxicity
15 µM
Hemolytic Cytotoxic
5% Hemolysis | 15 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Beta-sheet pore-forming peptides selected from a rational combinatorial library: mechanism of pore formation in lipid vesicles and activity in biological membranes. | Biochemistry | 2007
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis