Back to search

Peptide record

TPDB10757

Antibacterial Antifungal Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10757
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RRGAGLGLALAKDGWALMLKLGFGRR
Physicochemical Analysis
C125H211N41O29S1
NCEQHIPSTYV
GL
2784.37
12.41
6
1
13
+5
-0.74
0.081
105.38
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
197.53
0
Residue Composition
number
4
A
4
R
0
N
1
D
0
C
0
E
0
Q
6
G
0
H
0
I
6
L
2
K
1
M
1
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 4 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 6 H: 0 I: 0 L: 6 K: 2 M: 1 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
26
C125H211N41O29S1
2784.37
12.41
+5
-0.74
0.081
Evidence Records 3 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
15 µM
Hemolytic Cytotoxic
5% Hemolysis | 15 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Beta-sheet pore-forming peptides selected from a rational combinatorial library: mechanism of pore formation in lipid vesicles and activity in biological membranes. | Biochemistry | 2007
Evidence 2 Activity

Activity

45% Hemolysis
Toxicity
15 µM
Hemolytic Cytotoxic
45% Hemolysis | 15 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Beta-sheet pore-forming peptides selected from a rational combinatorial library: mechanism of pore formation in lipid vesicles and activity in biological membranes. | Biochemistry | 2007
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis