Peptide record

TPDB10736

Antibacterial Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10736
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KWKSFLKTFKSAKKKVLHTALKAISS
Physicochemical Analysis
C141H235N37O33
RNDCEQGMPY
K
2976.65
11.36
9
0
11
+8
3.14
-0.338
82.69
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
184.77
6
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
3
L
8
K
0
M
2
F
0
P
4
S
2
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 3 K: 8 M: 0 F: 2 P: 0 S: 4 T: 2 W: 1 Y: 0 V: 1
Chemical Descriptors
26
C141H235N37O33
2976.65
11.36
+8
3.14
-0.338
Evidence Records 2 records
Evidence 1 Activity

Activity

6% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
6% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent antimicrobial peptides with selectivity for Bacillus anthracis over human erythrocytes. | Int J Antimicrob Agents | 2011
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis