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Peptide record

TPDB10713

Antibacterial Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10713
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
GIGAVLKVLTTGLPACISWCKRKRQQ
Physicochemical Analysis
C125H216N38O32S2
NDEHMFY
GLK
2827.45
10.82
5
0
10
+5
1.81
0.146
105.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5625
198.94
7
Residue Composition
number
2
A
2
R
0
N
0
D
2
C
0
E
2
Q
3
G
0
H
2
I
3
L
3
K
0
M
0
F
1
P
1
S
2
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 2 E: 0 Q: 2 G: 3 H: 0 I: 2 L: 3 K: 3 M: 0 F: 0 P: 1 S: 1 T: 2 W: 1 Y: 0 V: 2
Chemical Descriptors
26
C125H216N38O32S2
2827.45
10.82
+5
1.81
0.146
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
5 µM
Hemolytic Cytotoxic
10% Hemolysis | 5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Reduction of helical content by insertion of a disulfide bond leads to an antimicrobial peptide with decreased hemolytic activity. | ChemMedChem | 2013
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
8 µM
Hemolytic Cytotoxic
10% Hemolysis | 8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Reduction of helical content by insertion of a disulfide bond leads to an antimicrobial peptide with decreased hemolytic activity. | ChemMedChem | 2013
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis