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Peptide record

TPDB10712

Antibacterial Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10712
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
GIGAVLKVLTTGLCALISWIKRKRQQ
Physicochemical Analysis
C129H226N38O32S1
NDEHMFPY
L
2853.51
11.56
5
0
12
+5
0.73
0.431
135.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
192.75
6
Residue Composition
number
2
A
2
R
0
N
0
D
1
C
0
E
2
Q
3
G
0
H
3
I
4
L
3
K
0
M
0
F
0
P
1
S
2
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 1 E: 0 Q: 2 G: 3 H: 0 I: 3 L: 4 K: 3 M: 0 F: 0 P: 0 S: 1 T: 2 W: 1 Y: 0 V: 2
Chemical Descriptors
26
C129H226N38O32S1
2853.51
11.56
+5
0.73
0.431
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
2.5 µM
Hemolytic Cytotoxic
50% Hemolysis | 2.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Melittin peptides exhibit different activity on different cells and model membranes. | Amino Acids | 2014
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
1 µM
Hemolytic Cytotoxic
50% Hemolysis | 1 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Melittin peptides exhibit different activity on different cells and model membranes. | Amino Acids | 2014
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis