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Peptide record

TPDB10703

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB10703
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb APD_complete APD_hemolytic Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIWGTALKWGVKLLPKLVGMAQTKKQ
Physicochemical Analysis
C134H223N35O31S1
RNDCEHFSY
K
2852.52
11.12
5
0
12
+5
0.20
0.027
105.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
385.62
4
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
2
Q
4
G
0
H
1
I
4
L
5
K
1
M
0
F
1
P
0
S
2
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 4 H: 0 I: 1 L: 4 K: 5 M: 1 F: 0 P: 1 S: 0 T: 2 W: 2 Y: 0 V: 2
Chemical Descriptors
26
C134H223N35O31S1
2852.52
11.12
+5
0.20
0.027
Evidence Records 4 records
Evidence 1 Activity

Activity

Hemolysis
[Ref.11279030]2mm in test condition against horse erythrocytes (A 12-ml sample of blood agar medium was supplemented with 1 ml of sheep or horse erythrocytes. Wells 5 mm in diameter were filled with 20 µl of the peptide solution and placed overnight at 4℃ to allow the diffusion of the hemolytic agent)

Target

horse erythrocytes

Source & Reference

Hemolytik APD_complete APD_hemolytic PD_Hemolysis
DRAMP4
J. Biol. Chem. 2001 276: 17823-17829.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Ponericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii. | J Biol Chem | 2001
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.11279030]2mm in test condition against horse erythrocytes (A 12-ml sample of blood agar medium was supplemented with 1 ml of sheep or horse erythrocytes. Wells 5 mm in diameter were filled with 20 µl of the peptide solution and placed overnight at 4℃ to allow the diffusion of the hemolytic agent)

Target

erythrocytes

Source & Reference

NA
DRAMP
J. Biol. Chem. 2001 276: 17823-17829.
Evidence 4 Hemolysis

Activity

[Ref.11279030]2mm in test condition against horse erythrocytes (A 12-ml sample of blood agar medium was supplemented with 1 ml of sheep or horse erythrocytes. Wells 5 mm in diameter were filled with 20 µl of the peptide solution and placed overnight at 4℃ to allow the diffusion of the hemolytic agent)
Hemolysis

Target

horse erythrocytes

Source & Reference

APD_complete APD_hemolytic PD_Hemolysis
J. Biol. Chem. 2001 276: 17823-17829.
DRAMP4
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.