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Peptide record

TPDB10675

Antibacterial Antifungal Hemolysis Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10675
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb PD_Hemolysis
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
IKRFWPVVIRTVVAGYNLYRAIKKK
Physicochemical Analysis
C145H236N40O30
DCEQHMS
KV
3019.72
11.57
7
0
14
+7
1.00
0.068
116.80
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
8480
280.82
4
Residue Composition
number
2
A
3
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
1
L
4
K
0
M
1
F
1
P
0
S
1
T
1
W
2
Y
4
V
Amino Acid Distribution
A: 2 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 1 K: 4 M: 0 F: 1 P: 1 S: 0 T: 1 W: 1 Y: 2 V: 4
Chemical Descriptors
25
C145H236N40O30
3019.72
11.57
+7
1.00
0.068
Evidence Records 4 records
Evidence 1 Activity

Activity

21% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
21% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1 | Nat Prod Bioprospect | 2012
Evidence 2 Activity

Activity

16% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
16% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1 | Nat Prod Bioprospect | 2012
Evidence 3 Activity

Activity

10% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1 | Nat Prod Bioprospect | 2012
Evidence 4 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis