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Peptide record

TPDB10670

EA Cathelicidin 1 EA-CATH1 Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10670
EA Cathelicidin 1 EA-CATH1
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia ACP740 _ACP240 AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0 DBAASP
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
KRRGSVTTRYQFLMIHLLRPKKLFA
Physicochemical Analysis
C141H235N43O31S1
NDCEW
RL
3060.75
12.42
8
0
11
+7
2.54
-0.348
93.60
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
48.68
5
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
0
E
1
Q
1
G
1
H
1
I
4
L
3
K
1
M
2
F
1
P
1
S
2
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 1 I: 1 L: 4 K: 3 M: 1 F: 2 P: 1 S: 1 T: 2 W: 0 Y: 1 V: 1
Chemical Descriptors
25
C141H235N43O31S1
3060.75
12.42
+7
2.54
-0.348
Evidence Records 2 records
Evidence 1 Activity

Activity

1.8% Hemolysis
Toxicity
20 µg/mL
Hemolytic Cytotoxic
1.8% Hemolysis | 20 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel cathelicidin-derived antimicrobial peptides from Equus asinus. | FEBS J | 2010
Evidence 2 Activity

Target

Cutibacterium acnes

Source & Reference

DBAASP