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Peptide record

TPDB10667

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10667
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb AVPpred-BWR
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SMISVLKNLGKVGLGFVACKVNKQC
Physicochemical Analysis
C116H202N32O31S3
RDEHPTWY
KV
2637.26
10.17
4
0
11
+4
1.95
0.612
112.80
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
4.74
7
Residue Composition
number
1
A
0
R
2
N
0
D
2
C
0
E
1
Q
3
G
0
H
1
I
3
L
4
K
1
M
1
F
0
P
2
S
0
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 0 C: 2 E: 0 Q: 1 G: 3 H: 0 I: 1 L: 3 K: 4 M: 1 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 4
Chemical Descriptors
25
C116H202N32O31S3
2637.26
10.17
+4
1.95
0.612
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
60 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus (MIC 60 uM), E. coli (MIC 3.5 uM), and C. albicans (MIC 110 uM). Updated 5/2018.
Evidence 2 Activity

Activity

MIC
Antibacterial
3.5 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus (MIC 60 uM), E. coli (MIC 3.5 uM), and C. albicans (MIC 110 uM). Updated 5/2018.
Evidence 3 Activity

Activity

MIC
Antibacterial
110 µM

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus (MIC 60 uM), E. coli (MIC 3.5 uM), and C. albicans (MIC 110 uM). Updated 5/2018.
Evidence 4 Activity

Activity

MIC
Antifungal
60 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus (MIC 60 uM), E. coli (MIC 3.5 uM), and C. albicans (MIC 110 uM). Updated 5/2018.
Evidence 5 Activity

Activity

MIC
Antifungal
3.5 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against S. aureus (MIC 60 uM), E. coli (MIC 3.5 uM), and C. albicans (MIC 110 uM). Updated 5/2018.
Evidence 6 Activity

Activity

MIC
Antifungal
110 µM

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against S. aureus (MIC 60 uM), E. coli (MIC 3.5 uM), and C. albicans (MIC 110 uM). Updated 5/2018.
Evidence 7 Activity

Activity

MIC
Antiparasitic
60 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus (MIC 60 uM), E. coli (MIC 3.5 uM), and C. albicans (MIC 110 uM). Updated 5/2018.
Evidence 8 Activity

Activity

MIC
Antiparasitic
3.5 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Active against S. aureus (MIC 60 uM), E. coli (MIC 3.5 uM), and C. albicans (MIC 110 uM). Updated 5/2018.
Evidence 9 Activity

Activity

MIC
Antiparasitic
110 µM

Target

Candida albicans

Source & Reference

DRAMP

Other

Active against S. aureus (MIC 60 uM), E. coli (MIC 3.5 uM), and C. albicans (MIC 110 uM). Updated 5/2018.
Evidence 10 Activity

Activity

MIC
Antiviral
60 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against S. aureus (MIC 60 uM), E. coli (MIC 3.5 uM), and C. albicans (MIC 110 uM). Updated 5/2018.
Evidence 11 Activity

Activity

MIC
Antiviral
3.5 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Active against S. aureus (MIC 60 uM), E. coli (MIC 3.5 uM), and C. albicans (MIC 110 uM). Updated 5/2018.
Evidence 12 Activity

Activity

MIC
Antiviral
110 µM

Target

Candida albicans

Source & Reference

DRAMP

Other

Active against S. aureus (MIC 60 uM), E. coli (MIC 3.5 uM), and C. albicans (MIC 110 uM). Updated 5/2018.