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Peptide record

TPDB10661

Antibacterial Anticancer Antifungal Antiparasitic standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10661
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LSCKRGTCHFGRCPSHLIKGSCSGG
Physicochemical Analysis
C106H175N37O31S4
ANDEQMWYV
G
2592.02
9.29
6
0
4
+4
3.16
-0.232
46.80
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
250
9.64
9
Residue Composition
number
0
A
2
R
0
N
0
D
4
C
0
E
0
Q
5
G
2
H
1
I
2
L
2
K
0
M
1
F
1
P
4
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 5 H: 2 I: 1 L: 2 K: 2 M: 0 F: 1 P: 1 S: 4 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
25
C106H175N37O31S4
2592.02
9.29
+4
3.16
-0.232
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against C. albicans (MIC 16 ug/ml), B-avium (MIC >16 ug/ml), E-coli (MIC >16 ug/ml), S. enteriditis (MIC 8 ug/ml), S-typhimu
Evidence 2 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

S. enteriditis

Source & Reference

dbAMP DRAMP

Other

tive against C. albicans (MIC 16 ug/ml), B-avium (MIC >16 ug/ml), E-coli (MIC >16 ug/ml), S. enteriditis (MIC 8 ug/ml), S-typhimurium (MIC >16 ug/ml), C. jejuni (MIC 16 ug/ml), P-multocida (MIC >16 ug/ml), M.
Evidence 3 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

C. jejuni

Source & Reference

dbAMP DRAMP

Other

ml), E-coli (MIC >16 ug/ml), S. enteriditis (MIC 8 ug/ml), S-typhimurium (MIC >16 ug/ml), C. jejuni (MIC 16 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 8 ug/ml) ( Evans et al., 1995 . THP3
Evidence 4 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

M. gallisepticum

Source & Reference

dbAMP DRAMP

Other

l), S-typhimurium (MIC >16 ug/ml), C. jejuni (MIC 16 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 8 ug/ml) ( Evans et al., 1995 . THP3 killed only S. aureus in vitro. Updated 7/2021, Jan2023
Evidence 5 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against C. albicans (MIC 16 ug/ml), B-avium (MIC >16 ug/ml), E-coli (MIC >16 ug/ml), S. enteriditis (MIC 8 ug/ml), S-typhimu
Evidence 6 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

S. enteriditis

Source & Reference

dbAMP DRAMP Antifungipept

Other

tive against C. albicans (MIC 16 ug/ml), B-avium (MIC >16 ug/ml), E-coli (MIC >16 ug/ml), S. enteriditis (MIC 8 ug/ml), S-typhimurium (MIC >16 ug/ml), C. jejuni (MIC 16 ug/ml), P-multocida (MIC >16 ug/ml), M.
Evidence 7 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

C. jejuni

Source & Reference

dbAMP DRAMP Antifungipept

Other

ml), E-coli (MIC >16 ug/ml), S. enteriditis (MIC 8 ug/ml), S-typhimurium (MIC >16 ug/ml), C. jejuni (MIC 16 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 8 ug/ml) ( Evans et al., 1995 . THP3
Evidence 8 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

M. gallisepticum

Source & Reference

dbAMP DRAMP Antifungipept

Other

l), S-typhimurium (MIC >16 ug/ml), C. jejuni (MIC 16 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 8 ug/ml) ( Evans et al., 1995 . THP3 killed only S. aureus in vitro. Updated 7/2021, Jan2023
Evidence 9 Activity

Activity

MIC
Antiparasitic
16 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
active against C. albicans (MIC 16 ug/ml), B-avium (MIC >16 ug/ml), E-coli (MIC >16 ug/ml), S. enteriditis (MIC 8 ug/ml), S-typhimu
Evidence 10 Activity

Activity

MIC
Antiparasitic
8 µg/mL

Target

S. enteriditis

Source & Reference

DRAMP

Other

tive against C. albicans (MIC 16 ug/ml), B-avium (MIC >16 ug/ml), E-coli (MIC >16 ug/ml), S. enteriditis (MIC 8 ug/ml), S-typhimurium (MIC >16 ug/ml), C. jejuni (MIC 16 ug/ml), P-multocida (MIC >16 ug/ml), M.
Evidence 11 Activity

Activity

MIC
Antiparasitic
16 µg/mL

Target

C. jejuni

Source & Reference

DRAMP

Other

ml), E-coli (MIC >16 ug/ml), S. enteriditis (MIC 8 ug/ml), S-typhimurium (MIC >16 ug/ml), C. jejuni (MIC 16 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 8 ug/ml) ( Evans et al., 1995 . THP3
Evidence 12 Activity

Activity

MIC
Antiparasitic
8 µg/mL

Target

M. gallisepticum

Source & Reference

DRAMP

Other

l), S-typhimurium (MIC >16 ug/ml), C. jejuni (MIC 16 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 8 ug/ml) ( Evans et al., 1995 . THP3 killed only S. aureus in vitro. Updated 7/2021, Jan2023