Peptide record

TPDB10656

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10656
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept AI4AVP dbAMP 3.0 DRAVP 2.0 ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GAWKNFWSSLRKGFYDGEAGRAIRR
Physicochemical Analysis
C133H198N42O34
CQHMPTV
RG
2929.30
11.34
6
2
10
+4
0.91
-0.932
43.20
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12490
426.38
4
Residue Composition
number
3
A
4
R
1
N
1
D
0
C
1
E
0
Q
4
G
0
H
1
I
1
L
2
K
0
M
2
F
0
P
2
S
0
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 3 R: 4 N: 1 D: 1 C: 0 E: 1 Q: 0 G: 4 H: 0 I: 1 L: 1 K: 2 M: 0 F: 2 P: 0 S: 2 T: 0 W: 2 Y: 1 V: 0
Chemical Descriptors
25
C133H198N42O34
2929.30
11.34
+4
0.91
-0.932
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
>34.1 µM
Cytotoxic
50% Cell death | >34.1 | µM | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. | Antimicrob Agents Chemother | 2010