Back to search

Peptide record

TPDB10654

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10654
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AFP-GFuse Antifungipept CAFPdb i2APP AI4AVP dbAMP 3.0 DRAVP 2.0 ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
HVDKKVADKVLLLKQLRIMRLLTRL
Physicochemical Analysis
C136H247N41O32S1
NCEGFPSWY
L
3000.77
11.53
8
2
13
+5
6.11
0.156
163.60
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
3
R
0
N
2
D
0
C
0
E
1
Q
0
G
1
H
1
I
7
L
4
K
1
M
0
F
0
P
0
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 2 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 1 L: 7 K: 4 M: 1 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
25
C136H247N41O32S1
3000.77
11.53
+5
6.11
0.156
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Solution structure of termite-derived antimicrobial peptide, spinigerin, as determined in SDS micelle by NMR spectroscopy. | Biochem Biophys Res Commun | 2003
Evidence 2 Activity

Activity

50% Cell death
Toxicity
>33.3 µM
Cytotoxic
50% Cell death | >33.3 | µM | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. | Antimicrob Agents Chemother | 2010
Evidence 3 Activity

Activity

1% Hemolysis
Toxicity
6.3 µM
Hemolytic Cytotoxic
1% Hemolysis | 6.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterisation and evaluation of synthetic antimicrobial peptides against Bacillus globigii, Bacillus anthracis and Burkholderia thailandensis. | Int J Antimicrob Agents | 2010