Peptide record

TPDB10627

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10627
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GIGGALLSAGKSALKGLAKGLAEHF
Physicochemical Analysis
C107H180N30O30
RNDCQMPTWYV
G
2366.79
10.32
4
1
12
+2
1.18
0.516
113.60
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
5
A
0
R
0
N
0
D
0
C
1
E
0
Q
6
G
1
H
1
I
5
L
3
K
0
M
1
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 6 H: 1 I: 1 L: 5 K: 3 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
25
C107H180N30O30
2366.79
10.32
+2
1.18
0.516
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 37.5 ug/ml), E. coli ATCC 25922 (MIC 75 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
75 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 37.5 ug/ml), E. coli ATCC 25922 (MIC 75 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

dbAMP

Other

100 ug/ml), S. aureus ATCC 25923 (MIC 37.5 ug/ml), E. coli ATCC 25922 (MIC 75 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 4 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 37.5 ug/ml), E. coli ATCC 25922 (MIC 75 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 5 Activity

Activity

MIC
Antifungal
75 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 37.5 ug/ml), E. coli ATCC 25922 (MIC 75 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

100 ug/ml), S. aureus ATCC 25923 (MIC 37.5 ug/ml), E. coli ATCC 25922 (MIC 75 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 7 Activity

Activity

MIC
Antiparasitic
37.5 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 37.5 ug/ml), E. coli ATCC 25922 (MIC 75 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 8 Activity

Activity

MIC
Antiparasitic
75 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 37.5 ug/ml), E. coli ATCC 25922 (MIC 75 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 9 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

NA

Other

100 ug/ml), S. aureus ATCC 25923 (MIC 37.5 ug/ml), E. coli ATCC 25922 (MIC 75 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 10 Activity

Activity

MIC
Antiviral
37.5 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 37.5 ug/ml), E. coli ATCC 25922 (MIC 75 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 11 Activity

Activity

MIC
Antiviral
75 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 37.5 ug/ml), E. coli ATCC 25922 (MIC 75 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 12 Activity

Activity

MIC
Antiviral
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

NA

Other

100 ug/ml), S. aureus ATCC 25923 (MIC 37.5 ug/ml), E. coli ATCC 25922 (MIC 75 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 13 Activity

Activity

4% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
4% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 14 Activity

Activity

1% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 62.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 15 Activity

Activity

1% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 125 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 16 Activity

Activity

1% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 62.5 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011