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Peptide record

TPDB10592

Antibacterial Anticancer Antifungal Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10592
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 25-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
ADMDFTGIAESIIKKIKETNAKPPA
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C119H198N30O38S1
RCQHLWYV
AIK
2689.12
7.09
4
4
10
+0
1.41
-0.360
78.40
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
4
A
0
R
1
N
2
D
0
C
2
E
0
Q
1
G
0
H
4
I
0
L
4
K
1
M
1
F
2
P
1
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 2 C: 0 E: 2 Q: 0 G: 1 H: 0 I: 4 L: 0 K: 4 M: 1 F: 1 P: 2 S: 1 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
25 reviewed residue count
C119H198N30O38S1 sequence-only estimate (linear, free termini)
2689.12 sequence-only estimate (linear, free termini)
7.09 sequence-only estimate (linear, free termini)
+0 sequence-only estimate (linear, free termini)
1.41 sequence-only estimate (linear, free termini)
-0.360 sequence-only estimate (linear, free termini)
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Characterization of TistH, a multifunctional peptide from the scorpion Tityus stigmurus: Structure, cytotoxicity and antimicrobial activity | Toxicon | 2016
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Characterization of TistH, a multifunctional peptide from the scorpion Tityus stigmurus: Structure, cytotoxicity and antimicrobial activity | Toxicon | 2016
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Toxicon. 2016 Sep 1 119:362-70.