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Peptide record

TPDB10590

Antibacterial Hemolysis Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10590
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
FKRIVQRIKDFLRGIGKFLHSAKKF
Physicochemical Analysis
C144H234N42O30
NCEMPTWY
K
3033.71
12.17
9
1
11
+7
3.63
-0.260
93.60
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
1
A
3
R
0
N
1
D
0
C
0
E
1
Q
2
G
1
H
3
I
2
L
5
K
0
M
4
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 2 H: 1 I: 3 L: 2 K: 5 M: 0 F: 4 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
25
C144H234N42O30
3033.71
12.17
+7
3.63
-0.260
Evidence Records 3 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
100% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent antimicrobial peptides with selectivity for Bacillus anthracis over human erythrocytes. | Int J Antimicrob Agents | 2011
Evidence 2 Activity

Activity

90% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
90% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design and characterization of novel hybrid antimicrobial peptides based on cecropin A, LL-37 and magainin II. | Peptides | 2012
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis