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Peptide record

TPDB10577

Antibacterial Anticancer Hemolysis Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10577
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
GFIATLCTKVLDFGIDKLIQLIEDK
Physicochemical Analysis
C129H213N29O37S1
RNHMPSWY
IL
2794.34
4.45
3
4
12
-1
3.48
0.636
140.40
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
1
A
0
R
0
N
3
D
1
C
1
E
1
Q
2
G
0
H
4
I
4
L
3
K
0
M
2
F
0
P
0
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 3 C: 1 E: 1 Q: 1 G: 2 H: 0 I: 4 L: 4 K: 3 M: 0 F: 2 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
25
C129H213N29O37S1
2794.34
4.45
-1
3.48
0.636
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
10% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
10 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 10% Hemolysis=10 µm | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Proc Natl Acad Sci U S A. 1994 Mar 29 91(7):2602-6.
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis