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Peptide record

TPDB10561

Antibacterial Antifungal Hemolysis Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10561
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
SMLSVLKNLGKVGLGFVACKINKKC
Physicochemical Analysis
C118H208N32O30S3
RDEQHPTWY
K
2651.33
10.39
5
0
11
+5
1.73
0.580
116.80
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
4.71
6
Residue Composition
number
1
A
0
R
2
N
0
D
2
C
0
E
0
Q
3
G
0
H
1
I
4
L
5
K
1
M
1
F
0
P
2
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 0 C: 2 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 4 K: 5 M: 1 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
25
C118H208N32O30S3
2651.33
10.39
+5
1.73
0.580
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
80 µM
Hemolytic Cytotoxic
50% Hemolysis | 80 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial properties of the frog skin peptide, ranatuerin-1 and its [Lys-8]-substituted analog. | Peptides | 2004
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis