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Peptide record

TPDB10551

Antibacterial Antifungal Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10551
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FFGWLIKGAIHAPKAIHGLIHRRRH
Physicochemical Analysis
C139H215N45O26
NDCEQMSTYV
HI
2932.52
12.71
9
0
12
+5
1.75
-0.048
105.60
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
187.55
0
Residue Composition
number
3
A
3
R
0
N
0
D
0
C
0
E
0
Q
3
G
4
H
4
I
2
L
2
K
0
M
2
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 4 I: 4 L: 2 K: 2 M: 0 F: 2 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
25
C139H215N45O26
2932.52
12.71
+5
1.75
-0.048
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
30 µM
Hemolytic Cytotoxic
0% Hemolysis | 30 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of GXXXXG motif in Chrysophsin-1 and its implication in the design of analogs with cell-selective antimicrobial and anti-endotoxin activities. | Sci Rep | 2017
Evidence 2 Activity

Activity

8% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
8% Hemolysis | 40 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of GXXXXG motif in Chrysophsin-1 and its implication in the design of analogs with cell-selective antimicrobial and anti-endotoxin activities. | Sci Rep | 2017
Evidence 3 Activity

Activity

18% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
18% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of GXXXXG motif in Chrysophsin-1 and its implication in the design of analogs with cell-selective antimicrobial and anti-endotoxin activities. | Sci Rep | 2017