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Peptide record

TPDB10545

Antibacterial Hemolysis Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10545
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KWKKLLKKLLKLPKKLLKKLKKLLK
Physicochemical Analysis
C154H285N39O26
ARNDCEQGHIMFSTYV
K
3099.20
11.59
13
0
11
+13
5.87
-0.608
156.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
177.47
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
10
L
13
K
0
M
0
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 10 K: 13 M: 0 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
25
C154H285N39O26
3099.20
11.59
+13
5.87
-0.608
Evidence Records 2 records
Evidence 1 Activity

Activity

11% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
11% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Contribution of a central proline in model amphipathic alpha-helical peptides to self-association, interaction with phospholipids, and antimicrobial mode of action. | FASEB J | 2006
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis