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Peptide record

TPDB10542

Antibacterial Antifungal Antiparasitic Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10542
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept dbAMP 3.0 ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GVFDIIKGAGKQLIAHAMGKIAEKV
Physicochemical Analysis
C118H200N32O31S1
RNCPSTWY
AGIK
2595.14
10.16
5
2
13
+2
5.09
0.448
117.20
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
4
A
0
R
0
N
1
D
0
C
1
E
1
Q
4
G
1
H
4
I
1
L
4
K
1
M
1
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 1 G: 4 H: 1 I: 4 L: 1 K: 4 M: 1 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
25
C118H200N32O31S1
2595.14
10.16
+2
5.09
0.448
Evidence Records 14 records
Evidence 1 Activity

Activity

MIC
Antibacterial
80 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

it has leishmanicidal activity (IC50 9.8 uM). Weakly active against E. coli ATCC 25922 (MIC 80 uM), K.pneumoniae ATCC 700603 (MIC 310 uM), S.choleraesuis ATCC 14028 (MIC 310 uM), and S.aur
Evidence 2 Activity

Activity

MIC
Antibacterial
310 µM

Target

K.pneumoniae ATCC 700603

Source & Reference

NA

Other

shmanicidal activity (IC50 9.8 uM). Weakly active against E. coli ATCC 25922 (MIC 80 uM), K.pneumoniae ATCC 700603 (MIC 310 uM), S.choleraesuis ATCC 14028 (MIC 310 uM), and S.aureus ATCC 29313 (MIC >310 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
310 µM

Target

S.choleraesuis ATCC 14028

Source & Reference

NA

Other

kly active against E. coli ATCC 25922 (MIC 80 uM), K.pneumoniae ATCC 700603 (MIC 310 uM), S.choleraesuis ATCC 14028 (MIC 310 uM), and S.aureus ATCC 29313 (MIC >310 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
>310 µM

Target

S.aureus ATCC 29313

Source & Reference

NA

Other

0 uM), K.pneumoniae ATCC 700603 (MIC 310 uM), S.choleraesuis ATCC 14028 (MIC 310 uM), and S.aureus ATCC 29313 (MIC >310 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
80 µM

Target

Escherichia coli ATCC 25922

Source & Reference

Antifungipept

Other

it has leishmanicidal activity (IC50 9.8 uM). Weakly active against E. coli ATCC 25922 (MIC 80 uM), K.pneumoniae ATCC 700603 (MIC 310 uM), S.choleraesuis ATCC 14028 (MIC 310 uM), and S.aur
Evidence 6 Activity

Activity

MIC
Antifungal
310 µM

Target

K.pneumoniae ATCC 700603

Source & Reference

Antifungipept

Other

shmanicidal activity (IC50 9.8 uM). Weakly active against E. coli ATCC 25922 (MIC 80 uM), K.pneumoniae ATCC 700603 (MIC 310 uM), S.choleraesuis ATCC 14028 (MIC 310 uM), and S.aureus ATCC 29313 (MIC >310 uM).
Evidence 7 Activity

Activity

MIC
Antifungal
310 µM

Target

S.choleraesuis ATCC 14028

Source & Reference

Antifungipept

Other

kly active against E. coli ATCC 25922 (MIC 80 uM), K.pneumoniae ATCC 700603 (MIC 310 uM), S.choleraesuis ATCC 14028 (MIC 310 uM), and S.aureus ATCC 29313 (MIC >310 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
>310 µM

Target

S.aureus ATCC 29313

Source & Reference

Antifungipept

Other

0 uM), K.pneumoniae ATCC 700603 (MIC 310 uM), S.choleraesuis ATCC 14028 (MIC 310 uM), and S.aureus ATCC 29313 (MIC >310 uM).
Evidence 9 Activity

Activity

MIC
Antiparasitic
80 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
it has leishmanicidal activity (IC50 9.8 uM). Weakly active against E. coli ATCC 25922 (MIC 80 uM), K.pneumoniae ATCC 700603 (MIC 310 uM), S.choleraesuis ATCC 14028 (MIC 310 uM), and S.aur
Evidence 10 Activity

Activity

MIC
Antiparasitic
310 µM

Target

K.pneumoniae ATCC 700603

Source & Reference

dbAMP 3.0

Other

shmanicidal activity (IC50 9.8 uM). Weakly active against E. coli ATCC 25922 (MIC 80 uM), K.pneumoniae ATCC 700603 (MIC 310 uM), S.choleraesuis ATCC 14028 (MIC 310 uM), and S.aureus ATCC 29313 (MIC >310 uM).
Evidence 11 Activity

Activity

MIC
Antiparasitic
310 µM

Target

S.choleraesuis ATCC 14028

Source & Reference

dbAMP 3.0

Other

kly active against E. coli ATCC 25922 (MIC 80 uM), K.pneumoniae ATCC 700603 (MIC 310 uM), S.choleraesuis ATCC 14028 (MIC 310 uM), and S.aureus ATCC 29313 (MIC >310 uM).
Evidence 12 Activity

Activity

MIC
Antiparasitic
>310 µM

Target

S.aureus ATCC 29313

Source & Reference

dbAMP 3.0

Other

0 uM), K.pneumoniae ATCC 700603 (MIC 310 uM), S.choleraesuis ATCC 14028 (MIC 310 uM), and S.aureus ATCC 29313 (MIC >310 uM).
Evidence 13 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization and Biological Activities of Ocellatin Peptides from the Skin Secretion of the Frog Leptodactylus pustulatus. | J Nat Prod | 2015
Evidence 14 Activity

Activity

4% Hemolysis
Toxicity
800 µg/mL
Hemolytic Cytotoxic
4% Hemolysis | 800 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization and Biological Activities of Ocellatin Peptides from the Skin Secretion of the Frog Leptodactylus pustulatus. | J Nat Prod | 2015