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Peptide record

TPDB10537

Antibacterial Antifungal standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10537
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 25-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
FKIPPIVKDTLKKFFKGGIAGVMGQ
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C130H211N31O30S1
RNCEHSWY
K
2720.36
10.71
5
1
11
+4
-0.00
0.232
89.60
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
1
Q
4
G
0
H
3
I
1
L
5
K
1
M
3
F
2
P
0
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 4 H: 0 I: 3 L: 1 K: 5 M: 1 F: 3 P: 2 S: 0 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
25 reviewed residue count
C130H211N31O30S1 sequence-only estimate (linear, free termini)
2720.36 sequence-only estimate (linear, free termini)
10.71 sequence-only estimate (linear, free termini)
+4 sequence-only estimate (linear, free termini)
-0.00 sequence-only estimate (linear, free termini)
0.232 sequence-only estimate (linear, free termini)
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against S. aureus (MIC 5 uM) and E. coli (MIC 20 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
20 µM

Target

Escherichia coli

Source & Reference

NA

Other

Active against S. aureus (MIC 5 uM) and E. coli (MIC 20 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
5 µM

Target

Staphylococcus aureus

Source & Reference

Antifungipept

Other

Active against S. aureus (MIC 5 uM) and E. coli (MIC 20 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
20 µM

Target

Escherichia coli

Source & Reference

Antifungipept

Other

Active against S. aureus (MIC 5 uM) and E. coli (MIC 20 uM).