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Peptide record

TPDB10533

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10533
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLASTIGSLLGKFAKGGAQAFLQPK
Physicochemical Analysis
C113H186N30O31
RNDCEHMWYV
G
2460.90
10.84
3
0
11
+3
-0.46
0.316
94.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
2
Q
5
G
0
H
1
I
4
L
3
K
0
M
2
F
1
P
2
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 5 H: 0 I: 1 L: 4 K: 3 M: 0 F: 2 P: 1 S: 2 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
25
C113H186N30O31
2460.90
10.84
+3
-0.46
0.316
Evidence Records 14 records
Evidence 1 Activity

Activity

MIC
Antibacterial
100 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli (MIC 100 uM), A. baumannii (MIC 25 uM). Also E. coli (MIC>160 uM), S. aureus (MIC 80 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
25 µM

Target

A. baumannii

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 100 uM), A. baumannii (MIC 25 uM). Also E. coli (MIC>160 uM), S. aureus (MIC 80 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
>160 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 100 uM), A. baumannii (MIC 25 uM). Also E. coli (MIC>160 uM), S. aureus (MIC 80 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
80 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 100 uM), A. baumannii (MIC 25 uM). Also E. coli (MIC>160 uM), S. aureus (MIC 80 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
100 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli (MIC 100 uM), A. baumannii (MIC 25 uM). Also E. coli (MIC>160 uM), S. aureus (MIC 80 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
25 µM

Target

A. baumannii

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 100 uM), A. baumannii (MIC 25 uM). Also E. coli (MIC>160 uM), S. aureus (MIC 80 uM).
Evidence 7 Activity

Activity

MIC
Antifungal
>160 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 100 uM), A. baumannii (MIC 25 uM). Also E. coli (MIC>160 uM), S. aureus (MIC 80 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
80 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 100 uM), A. baumannii (MIC 25 uM). Also E. coli (MIC>160 uM), S. aureus (MIC 80 uM).
Evidence 9 Activity

Activity

MIC
Antiparasitic
100 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli (MIC 100 uM), A. baumannii (MIC 25 uM). Also E. coli (MIC>160 uM), S. aureus (MIC 80 uM).
Evidence 10 Activity

Activity

MIC
Antiparasitic
25 µM

Target

A. baumannii

Source & Reference

DRAMP

Other

Active against E. coli (MIC 100 uM), A. baumannii (MIC 25 uM). Also E. coli (MIC>160 uM), S. aureus (MIC 80 uM).
Evidence 11 Activity

Activity

MIC
Antiparasitic
>160 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Active against E. coli (MIC 100 uM), A. baumannii (MIC 25 uM). Also E. coli (MIC>160 uM), S. aureus (MIC 80 uM).
Evidence 12 Activity

Activity

MIC
Antiparasitic
80 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Active against E. coli (MIC 100 uM), A. baumannii (MIC 25 uM). Also E. coli (MIC>160 uM), S. aureus (MIC 80 uM).
Evidence 13 Activity

Activity

50% Hemolysis
Toxicity
>160 µM
Hemolytic Cytotoxic
50% Hemolysis | >160 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Host-defense peptides in skin secretions of the tetraploid frog Silurana epitropicalis with potent activity against methicillin-resistant Staphylococcus aureus (MRSA). | Peptides | 2012
Evidence 14 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.