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Peptide record

TPDB10521

Antibacterial Antifungal Hemolysis Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10521
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
SMLSVLKNLGKVGLGFVASKINKQS
Physicochemical Analysis
C117H204N32O33S1
RDCEHPTWY
LKS
2619.16
11.00
4
0
11
+4
2.06
0.332
116.80
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
7
Residue Composition
number
1
A
0
R
2
N
0
D
0
C
0
E
1
Q
3
G
0
H
1
I
4
L
4
K
1
M
1
F
0
P
4
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 1 L: 4 K: 4 M: 1 F: 1 P: 0 S: 4 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
25
C117H204N32O33S1
2619.16
11.00
+4
2.06
0.332
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial properties of the frog skin peptide, ranatuerin-1 and its [Lys-8]-substituted analog. | Peptides | 2004
Evidence 2 Activity

Activity

33% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
33% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial properties of the frog skin peptide, ranatuerin-1 and its [Lys-8]-substituted analog. | Peptides | 2004
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis