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Peptide record

TPDB10496

Antibacterial Hemolysis Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB10496
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
FWGALAKGALKLIVGSLFSSFSKKD
Physicochemical Analysis
C128H200N30O32
RNCEQHMPTY
LKS
2671.18
10.55
4
1
13
+3
-2.49
0.532
101.60
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
205.90
4
Residue Composition
number
3
A
0
R
0
N
1
D
0
C
0
E
0
Q
3
G
0
H
1
I
4
L
4
K
0
M
3
F
0
P
4
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 4 K: 4 M: 0 F: 3 P: 0 S: 4 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
25
C128H200N30O32
2671.18
10.55
+3
-2.49
0.532
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
8.8 µM
Hemolytic Cytotoxic
50% Hemolysis | 8.8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Amino acid substitutions in an alpha-helical antimicrobial arachnid peptide affect its chemical properties and biological activity towards pathogenic bacteria but improves its therapeutic index. | Amino Acids | 2011
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis