TPDB

3D PDB MODEL

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TPDB ID TPDB10483

Activity

Antibacterial Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP

Sequence_Type

standard

Has_Modification No

Description A 24-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.

Sequence

FLPILAGLAANLVPKLICSITKKC

FASTA

>TPDB10483|Antibacterial;Antifungal|length=24
FLPILAGLAANLVPKLICSITKKC

Formula C118H204N28O28S2

Absent Amino Acids RDEQHMWY

Common Amino Acids L

Mass 2527.21

PI 9.80

Basic Residues 3

Acidic Residues 0

Hydrophobic Residues 13

Net Charge +3

Boman Index -1.21

Hydrophobicity 1.233

Aliphatic Index 154.58

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 125

Absorbance 280nm 4.95

Polar Residues 5

number

3

A

0

R

1

N

0

D

2

C

0

E

0

Q

1

G

0

H

3

I

5

L

3

K

0

M

1

F

2

P

1

S

1

T

0

W

0

Y

1

V

Amino Acid Distribution

A: 3 R: 0 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 5 K: 3 M: 0 F: 1 P: 2 S: 1 T: 1 W: 0 Y: 0 V: 1

Length

24

Formula

C118H204N28O28S2

Mass

2527.21

PI

9.80

Net Charge

+3

Boman Index

-1.21

Hydrophobicity

1.233

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 12.5 µM

Target

Target Organism B. dendrobatidis Bd

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.

Evidence Text

Active against fungal pathogens B. dendrobatidis Bd (MIC 12.5 uM) and B. salamandrivorans (MIC 12.5 uM).

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 12.5 µM

Target

Target Organism B. salamandrivorans

Source & Reference

Database Source dbAMP

Other

Evidence Text

Active against fungal pathogens B. dendrobatidis Bd (MIC 12.5 uM) and B. salamandrivorans (MIC 12.5 uM).

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 12.5 µM

Target

Target Organism B. dendrobatidis Bd

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.

Evidence Text

Active against fungal pathogens B. dendrobatidis Bd (MIC 12.5 uM) and B. salamandrivorans (MIC 12.5 uM).

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 12.5 µM

Target

Target Organism B. salamandrivorans

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

Active against fungal pathogens B. dendrobatidis Bd (MIC 12.5 uM) and B. salamandrivorans (MIC 12.5 uM).