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Peptide record

TPDB10474

Antibacterial Antifungal Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10474
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP PD_Hemolysis
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
FLPLIAGLAAKFLPKIFCAITKKC
Physicochemical Analysis
C127H208N28O26S2
RNDEQHMSWYV
ALK
2607.34
10.17
4
0
14
+4
-2.71
1.225
130.42
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.79
3
Residue Composition
number
4
A
0
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
3
I
4
L
4
K
0
M
3
F
2
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 4 K: 4 M: 0 F: 3 P: 2 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C127H208N28O26S2
2607.34
10.17
+4
-2.71
1.225
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
1.576 µM
Hemolytic Cytotoxic
10% Hemolysis | 1.576 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Modification and Targeted Design of N-Terminal Truncates Derived from Brevinin with Improved Therapeutic Efficacy | Biology (Basel) | 2020
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis