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Peptide record

TPDB10468

Antibacterial Antifungal Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10468
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GLKALKKVFQGIHKAIKLINNHVQ
Physicochemical Analysis
C125H213N37O29
RDCEMPSTWY
K
2698.30
11.12
7
0
11
+5
4.95
-0.042
130.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
2
A
0
R
2
N
0
D
0
C
0
E
2
Q
2
G
2
H
3
I
3
L
5
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 2 G: 2 H: 2 I: 3 L: 3 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
24
C125H213N37O29
2698.30
11.12
+5
4.95
-0.042
Evidence Records 3 records
Evidence 1 Activity

Activity

25% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
25% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent antimicrobial peptides with selectivity for Bacillus anthracis over human erythrocytes. | Int J Antimicrob Agents | 2011
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
50% Hemolysis | 250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of potent, non-toxic antimicrobial agents based upon the structure of the frog skin peptide, pseudin-2. | Regul Pept | 2005
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis