Peptide record

TPDB10459

Antibacterial Anticancer Antifungal Antiparasitic standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10459
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLPLLAGLAANFLPKIFCKITKKC
Physicochemical Analysis
C128H209N29O27S2
RDEQHMSWYV
L
2650.37
10.17
4
0
13
+4
-2.37
0.975
126.25
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.72
4
Residue Composition
number
3
A
0
R
1
N
0
D
2
C
0
E
0
Q
1
G
0
H
2
I
5
L
4
K
0
M
3
F
2
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 5 K: 4 M: 0 F: 3 P: 2 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C128H209N29O27S2
2650.37
10.17
+4
-2.37
0.975
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
25 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli ATCC 25922 (MIC 25 uM), S. aureus NCTC 8325 (MIC 12.5 uM). Updated 2/2020 8/2025 GW
Evidence 2 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Staphylococcus aureus NCTC 8325

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC 25922 (MIC 25 uM), S. aureus NCTC 8325 (MIC 12.5 uM). Updated 2/2020 8/2025 GW
Evidence 3 Activity

Activity

MIC
Antifungal
25 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli ATCC 25922 (MIC 25 uM), S. aureus NCTC 8325 (MIC 12.5 uM). Updated 2/2020 8/2025 GW
Evidence 4 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Staphylococcus aureus NCTC 8325

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against E. coli ATCC 25922 (MIC 25 uM), S. aureus NCTC 8325 (MIC 12.5 uM). Updated 2/2020 8/2025 GW
Evidence 5 Activity

Activity

MIC
Antiparasitic
25 µM

Target

Escherichia coli ATCC 25922

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli ATCC 25922 (MIC 25 uM), S. aureus NCTC 8325 (MIC 12.5 uM). Updated 2/2020 8/2025 GW
Evidence 6 Activity

Activity

MIC
Antiparasitic
12.5 µM

Target

Staphylococcus aureus NCTC 8325

Source & Reference

DRAMP

Other

Active against E. coli ATCC 25922 (MIC 25 uM), S. aureus NCTC 8325 (MIC 12.5 uM). Updated 2/2020 8/2025 GW