Back to search

Peptide record

TPDB10451

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10451
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLPLLAGVVANFLPQIICKIARKC
Physicochemical Analysis
C124H207N31O27S2
DEHMSTWY
L
2628.32
9.92
3
0
14
+3
-1.58
1.258
150.42
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.76
4
Residue Composition
number
3
A
1
R
1
N
0
D
2
C
0
E
1
Q
1
G
0
H
3
I
4
L
2
K
0
M
2
F
2
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 1 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 1 H: 0 I: 3 L: 4 K: 2 M: 0 F: 2 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
24
C124H207N31O27S2
2628.32
9.92
+3
-1.58
1.258
Evidence Records 8 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus ATCC2592, R. rhodochrous (Gram-poistive) and P. faecalis X29 (Gram-).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus ATCC2592, R. rhodochrous (Gram-poistive) and P. faecalis X29 (Gram-).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against S. aureus ATCC2592, R. rhodochrous (Gram-poistive) and P. faecalis X29 (Gram-).
Evidence 4 Activity

Activity

Antiviral

Source & Reference

DRAMP

Other

Active against S. aureus ATCC2592, R. rhodochrous (Gram-poistive) and P. faecalis X29 (Gram-).
Evidence 5 Activity

Activity

Hemolysis
[Ref.22100518]LD50=100 µg/ml against rabbit red blood cells

Target

rabbit red blood cells

Source & Reference

Hemolytik APD_complete PD_Hemolysis
DRAMP4
Peptides. 2012 Jan 33(1):27-34.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 6 Activity

Activity

50% Hemolysis
Toxicity
100.0 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 100.0 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of antimicrobial peptides from skin of Amolops ricketti (Anura: Ranidae). | Peptides | 2012
Evidence 7 Activity

Activity

LD50
Toxicity
100 µg/mL
Hemolytic
Hemolytic_activity: [Ref.22100518]LD50=100 µg/ml against rabbit red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2012 Jan 33(1):27-34.
Evidence 8 Hemolysis

Activity

[Ref.22100518]LD50=100 µg/ml against rabbit red blood cells
Hemolysis

Target

rabbit red blood cells

Source & Reference

APD_complete HemoPI PD_Hemolysis
Peptides. 2012 Jan 33(1):27-34.
DRAMP4
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.