Back to search

Peptide record

TPDB10437

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10437
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
IIPFVAGVAAEMMEHVYCAASKKC
Physicochemical Analysis
C114H182N28O31S4
RNDQLTW
A
2569.11
7.00
3
2
14
+0
3.30
0.838
89.58
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1615
62.86
4
Residue Composition
number
5
A
0
R
0
N
0
D
2
C
2
E
0
Q
1
G
1
H
2
I
0
L
2
K
2
M
1
F
1
P
1
S
0
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 2 E: 2 Q: 0 G: 1 H: 1 I: 2 L: 0 K: 2 M: 2 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 1 V: 3
Chemical Descriptors
24
C114H182N28O31S4
2569.11
7.00
+0
3.30
0.838
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
11.1 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 11.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
22.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

IC 11.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.2 ug/ml), Gram+ bacteria S. aureus (MIC 22.2 ug/ml), and yeast C. albicans (MIC 11.1 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
11.1 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

led P. aeruginosa) (MIC 22.2 ug/ml), Gram+ bacteria S. aureus (MIC 22.2 ug/ml), and yeast C. albicans (MIC 11.1 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
11.1 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 11.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
22.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

IC 11.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.2 ug/ml), Gram+ bacteria S. aureus (MIC 22.2 ug/ml), and yeast C. albicans (MIC 11.1 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
11.1 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

led P. aeruginosa) (MIC 22.2 ug/ml), Gram+ bacteria S. aureus (MIC 22.2 ug/ml), and yeast C. albicans (MIC 11.1 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
11.1 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 11.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
22.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

IC 11.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.2 ug/ml), Gram+ bacteria S. aureus (MIC 22.2 ug/ml), and yeast C. albicans (MIC 11.1 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
11.1 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 22.2 ug/ml), Gram+ bacteria S. aureus (MIC 22.2 ug/ml), and yeast C. albicans (MIC 11.1 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
11.1 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 11.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
22.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

IC 11.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 22.2 ug/ml), Gram+ bacteria S. aureus (MIC 22.2 ug/ml), and yeast C. albicans (MIC 11.1 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
11.1 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 22.2 ug/ml), Gram+ bacteria S. aureus (MIC 22.2 ug/ml), and yeast C. albicans (MIC 11.1 ug/ml). Updated 7/2021