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Peptide record

TPDB10411

Antibacterial Anticancer Antifungal Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10411
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ILELAGNAARDNKKTRIIPRHLQL
Physicochemical Analysis
C120H210N40O33
CMFSWYV
L
2741.24
11.37
6
2
10
+3
6.96
-0.442
126.25
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
4
Residue Composition
number
3
A
3
R
2
N
1
D
0
C
1
E
1
Q
1
G
1
H
3
I
4
L
2
K
0
M
0
F
1
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 3 N: 2 D: 1 C: 0 E: 1 Q: 1 G: 1 H: 1 I: 3 L: 4 K: 2 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C120H210N40O33
2741.24
11.37
+3
6.96
-0.442
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

Escherichia coli ML35p

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli ML35p (MIC 2.5 uM).
Evidence 2 Activity

Activity

MIC
Antifungal
2.5 µM

Target

Escherichia coli ML35p

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli ML35p (MIC 2.5 uM).
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
1-40 µM
Hemolytic Cytotoxic
0% Hemolysis | 1-40 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Acipensins - Novel Antimicrobial Peptides from Leukocytes of the Russian Sturgeon Acipenser gueldenstaedtii. | Acta Naturae | 2014